Hi Dean, sorry to hear about the mishap. I can't say for sure whether you'll be able to fix your Smoker port or not, it depends on what components were damaged. It almost sounds like this coincides with your connections problems, and if so that might indicate that something further upstream might have got fried as well, which would not be good.
But let's assume that is not the case. You can try replacing the smoker MOSFET and see if that fixes that port. Here is the part number and a link to DigiKey:
IPD090N03LGATMA1Fortunately it's a somewhat large part so shouldn't be too hard to unsolder and replace. I've highlighed the part in the image below.
As for the libusb0.dll error, rather than trying to update OP Config using its built-in updater, first uninstall OP Config from your computer (there should be an uninstall item in your OP Config folder in the Start Menu, but otherwise you can do it from Windows Add/Remove Programs).
Then go to the Downloads page and download the OP Config installer and run that. Maybe this re-install will fix your problem.